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Front cover illustration

Structure of Helicobacter pylori urease based on PDB data (PDB no. 1E9Z). Yellow, -subunit; white, -subunit; green, ureB138 regions; blue balls, nickel ions in the -subunit; red balls, histidine residues. Image courtesy Professor Taizo Uda, Prefectural University of Hiroshima, Japan. See the paper by Morihara et al. in this issue, pp. 847-853.