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The three images show the pattern of macrophage migration on an agar plate in response to the 57 kDa major antigenic outer-membrane protein of Shigella dysenteriae (upper), and in the presence of anti-CD3 mAb (middle) or anti-CD3 alone (lower) under bright-field illumination after Giemsa staining. The villous formation due to the effect of migration-activating factors released at 18 h can be observed. Image courtesy Dr A. K. Sinha, National Institute of Cholera & Enteric Diseases (ICMR), Beliaghata, Kolkata, India. See the paper by Sinha & Bagchi in this issue, pp. 1075--1081.

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