HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (Papers in Press[PDF]) All Versions of this Article: jmm.0.008391-0v1 58/7/959    most recent Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via CrossRef Google Scholar Articles by Gasparoto, T. H. Articles by Lara, V. S. PubMed PubMed Citation Articles by Gasparoto, T. H. Articles by Lara, V. S. Agricola Articles by Gasparoto, T. H. Articles by Lara, V. S.

Isolation of Candida dubliniensis in denture wearer individuals

University of São Paulo / Bauru School of Dentistry

¹ E-mail: cebola{at}usp.br

Received November 30, 2008
Accepted March 4, 2009

Candida albicans is considered the most important Candida species able to cause oral infections in denture wearers. In the last years, Candida dubliniensis has emerged as a pathogenic yeast in humans. The close phenotypic similarities between C. albicans and C. dubliniensis have led to the misidentification of these species. In this work, our aim was to verify through polymerase chain reaction the presence of C. dubliniensis in samples from palate and maxillary denture from 112 denture wearers presenting with or without denture-related stomatitis. C. dubliniensis was isolated at low rates from both palate (5.3% and 10.7%) and maxillary denture (5.3% and 8.9%) from wearers regardless of the presence of the disease. However, when C. dubliniensis was detected in individuals with denture-related stomatitis, it was always associated with C. albicans. In addition, our results showed that C. albicans was the most commonly identified candidal species on maxillary denture and hard palate of denture-related stomatitis patients (78.5% and 89.2%, respectively) as well as controls (31.2% and 28.5%, respectively). In conclusion, C. dubliniensis was detected in oral environment from denture wearer individuals. The association of C. dubliniensis with C. albicans occurred in approximately 10% of the denture-related stomatitis cases.