HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via CrossRef Citing Articles via Google Scholar Google Scholar Articles by VON EIFF, C. Articles by SPIEGEL, H.-U. Search for Related Content PubMed PubMed Citation Articles by VON EIFF, C. Articles by SPIEGEL, H.-U. Agricola Articles by VON EIFF, C. Articles by SPIEGEL, H.-U.

Bactericidal effect of extracorporeal shock waves on Staphylococcus aureus

C. VON EIFF, J. OVERBECK^*, G. HAUPT, M. HERRMANN, S. WINCKLER^*, K.-D. RICHTER, G. PETERS and H.-U. SPIEGEL

Institute of Medical Microbiology, *Department of Trauma- and Hand-Surgery, Central Animal Experimentation Facility, Department of General Surgery – Surgical Research, Westfälische Wilhelms-Universität Münster, 48149 Münster and Department of Urology, Ruhr-Universität Bochum, 44627 Herne, Germany

Corresponding author: Dr C. von Eiff (e-mail: eiffc{at}uni-muenster.de). Present address: Department of Urology, University of Cologne, 50924 Cologne, Germany.

Received 21 Oct. 1999; revised version received 9 Dec. 1999; accepted 22 Dec. 1999.

Abstract

Despite considerable knowledge about the effects of shock waves on eukaryotic soft tissues, no data are available concerning their effect on prokaryotic micro-organisms. In-vitro studies on the bactericidal effect of extracorporeal shock waves on staphylococci were performed with energy levels that are standard for the disintegration of calculi. Suspensions containing 10⁴--10⁵5mucfu of Staphylococcus aureus/ml were sealed in plastic tubes and exposed to shock waves, resulting in a mean decrease of 3.1 log₁₀. Whereas impulse rates of 350 resulted in a decrease of cfu/ml equalling the detection limit, lower numbers of impulses did not result in an appreciable bactericidal effect. The bactericidal effect of extracorporeal shock waves might provide the basis for the development of novel therapeutic strategies for bacterial infections.

This article has been cited by other articles:

				K.F. Novak, M. Govindaswami, J.L. Ebersole, W. Schaden, N. House, and M.J. Novak Effects of Low-energy Shock Waves on Oral Bacteria Journal of Dental Research, October 1, 2008; 87(10): 928 - 931. [Abstract] [Full Text] [PDF]

				S. Sathishkumar, A. Meka, D. Dawson, N. House, W. Schaden, M.J. Novak, J. L. Ebersole, and L. Kesavalu Extracorporeal Shock Wave Therapy Induces Alveolar Bone Regeneration Journal of Dental Research, July 1, 2008; 87(7): 687 - 691. [Abstract] [Full Text] [PDF]

				F.-S. Wang, C.-J. Wang, S.-M. Sheen-Chen, Y.-R. Kuo, R.-F. Chen, and K. D. Yang Superoxide Mediates Shock Wave Induction of ERK-dependent Osteogenic Transcription Factor (CBFA1) and Mesenchymal Cell Differentiation toward Osteoprogenitors J. Biol. Chem., March 22, 2002; 277(13): 10931 - 10937. [Abstract] [Full Text] [PDF]

				A. van Belkum and H. Verbrugh 40 years of methicillin resistant Staphylococcus aureus BMJ, September 22, 2001; 323(7314): 644 - 645. [Full Text] [PDF]