A safety and feasibility study comparing an intermittent high dose with a daily standard dose of liposomal amphotericin B for persistent neutropenic fever, by M. Ellis, R. Bernsen, H. Ali-Zadeh, J. Kristensen, U. Hedström, L. Poughias, M. Bresnik, A. Al-Essa & D. A. Stevens
Journal of Medical Microbiology vol. 58, part 11, pp. 1474 - 1485
Supplementary Tables S1-S5
[PDF file] (73 KB)
Supplementary Figs S1-S2 [PDF file] (327 KB)
Supplementary Fig. S1
Neutropenic profile for the two study groups. Median WBC, median white blood cell concentration.
Supplementary Fig. S2
Individual and median daily serum ALP (a), ALT (b) and AST (c) concentrations. Dashed lines indicate individual subjects. Grey horizontal lines indicate the ULN (a) or the ULN for males (upper) and females (lower) (b, c). Coloured lines show the results for individual subjects with persistent raised ALP (a), ALT (b) or AST (c) levels. Daily median values are indicated by a solid black line. Identified diagnoses are indicated by arrows.