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Molecular identification of Mycobacterium avium subspecies paratuberculosis in an Italian patient with Hashimoto's thyroiditis and Melkersson-Rosenthal syndrome

¹ University of Bari;

² University of Wisconsin

³ E-mail: s.lisi{at}anatomia.uniba.it

Received June 15, 2009
Accepted September 24, 2009

Recently we described the case of a 52-year-old woman with Melkersson-Rosenthal syndrome in association with Hashimoto's thyroiditis. In view of the literature supporting the involvement of Mycobacterium paratuberculosis(MAP)in autoimmune disease and an autoimmune etiology of MRS, we performed blood tests for the presence of MAP. The PCR data show a band that co-migrates with the positive control at the predicted 298 bp amplicon size. The sequenced DNA of the representative sample band showed 100 % identity with MAP IS900.