J Med Microbiol VLA Conference September 2010
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J Med Microbiol 59 (2010), 224-230; DOI: 10.1099/jmm.0.011593-0
© 2010 Society for General Microbiology
ISSN 0022-2615

Nocardia cyriacigeorgica: a case of endocarditis with disseminated soft-tissue infection

James S. Cargill{dagger},{ddagger}, Gavin J. Boyd{dagger} and Nigel C. Weightman

Department of Microbiology, Harrogate and District Hospital, Lancaster Park Road, Harrogate, North Yorkshire, HG2 7SX, UK

Correspondence
Nigel C. Weightman
nigel.weightman{at}hdft.nhs.uk

Received April 6, 2009
Accepted September 24, 2009

Nocardia cyriacigeorgica is a common environmental organism. It has been isolated from clinical samples in Europe, Asia and North America, predominantly from respiratory samples but also from samples from several other sites. We present a case report of an 85-year-old female patient in the UK who was found to have a multi-focal soft-tissue infection from which N. cyriacigeorgica was isolated. She had a background history of chronic obstructive pulmonary disease and corticosteroid use for polymyalgia rheumatica. During the course of her treatment echocardiography showed the presence of a mobile heart mass attached to a valve leaflet, a major Dukes criterion for endocarditis. We suggest that in cases of disseminated Nocardia infection, endocarditis should be tested for, particularly in cases failing to respond to treatment. We also review previous reports of both N. cyriacigeorgica infection, and of endocarditis due to Nocardia species and related genera.

{dagger}Present address: Department of Microbiology, Old Medical School, Leeds General Infirmary, Thoresby Place, Leeds LS1 3EX, UK.

{ddagger}Present address: Institute of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK.






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