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J Med Microbiol 58 (2009), 391-395; DOI: 10.1099/jmm.0.005942-0
© 2009 Society for General Microbiology
ISSN 0022-2615

Case Report

Phenotypic and genotypic characterization of Aspergillus lentulus and Aspergillus fumigatus isolates in a patient with probable invasive aspergillosis

Graciela Montenegro1, Silvia Sánchez Puch1, Virginia M. Jewtuchowicz1, Maria V. Pinoni1, Silvia Relloso1,2, Elena Temporitti2, Cristina A. Iovannitti1 and Maria T. Mujica1

1 Departamento de Microbiología, Parasitología e Inmunología, Facultad de Medicina, Universidad de Buenos Aires, Paraguay 2150, Piso 11 (1121), Buenos Aires, Argentina

2 Centro de Educación Médica e Investigaciones Clínicas ‘Dr. Norberto Quirno’ (CEMIC), Buenos Aires, Argentina

Correspondence
Maria T. Mujica
mtmujica{at}gmail.com

Received August 16, 2008
Accepted November 21, 2008

Characteristic morphological and phylogenetic analyses demonstrated the presence of Aspergillus fumigatus and Aspergillus lentulus as the aetiological agents in a case of probable invasive aspergillosis (IA). This is believed to be the first report of an A. lentulus strain isolated from a patient with probable IA in Argentina.

Abbreviations: AMB, amphotericin B; BAL, bronchoalveolar lavage; CAS, caspofungin; IA, invasive aspergillosis; ITS, internal transcribed spacer; VRZ, voriconazole.

The GenBank/EMBL/DDBJ accession numbers for the benA, rodA, mtcytb and ITS sequences of Aspergillus reported in this study are EU254411, EU254412, EU254414 and EU254413 for RS : B2007AR, and EU254415, EU254416, EU254418 and EU254417 for RS : V2007AR.






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