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J Med Microbiol 58 (2009), 386-390; DOI: 10.1099/jmm.0.003970-0
© 2009 Society for General Microbiology
ISSN 0022-2615

Case Report

Multifocal osteomyelitis caused by Candida dubliniensis

Nele Wellinghausen1, Angelika Moericke1, Silke Bundschuh2, Wilhelm Friedrich2, Ansgar S. Schulz2 and Susanne A. Gatz2

1 Institute of Medical Microbiology and Hygiene, University Hospital of Ulm, Ulm, Germany

2 University Hospital for Children's and Adolescent Medicine, Ulm, Germany

Correspondence
Nele Wellinghausen
nele.wellinghausen{at}web.de

Received June 4, 2008
Accepted November 20, 2008

Candida dubliniensis is an emerging fungal pathogen, especially in immunodeficient patients. We report what is to the best of our knowledge the first case of multifocal osteomyelitis following disseminated infection in a patient after haematopoietic stem cell transplantation. PFGE for typing of C. dubliniensis was developed and the necessity of long-term antifungal therapy is discussed.

Abbreviations: CrP, C-reactive protein; CSF, cerebrospinal fluid; CT, computed tomography; IHA, indirect haemagglutination; MRI, magnetic resonance imaging; PBSCT, peripheral blood stem cell transplantation; PET-CT, positron-emission-tomography computed tomography.






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