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J Med Microbiol 58 (2009), 82-85; DOI: 10.1099/jmm.0.003426-0
© 2009 Society for General Microbiology
ISSN 0022-2615

Characterization and genotyping of strains of Francisella tularensis isolated in Bulgaria

Krustyu T. Marinov1, Elena D. Georgieva1, Ivan N. Ivanov2 and Todor V. Kantardjiev2

1 Military Medical Academy, Georgy Sofiisky Blvd 3, Sofia, Bulgaria

2 National Centre of Infectious and Parasitic Diseases, Sofia, Bulgaria

Correspondence
Krustyu T. Marinov
krustju_marinov{at}yahoo.com

Received May 13, 2008
Accepted August 30, 2008

A tularaemia focus was detected in 1998 in Bulgaria, in an area where tularaemia had never been reported. The properties of Francisella tularensis subsp. holarctica strains isolated from 1998 to 2005 were studied. The strains showed heterogeneity, based on acid production from glycerol and erythromycin susceptibility. Genotyping by analysis of seven loci containing variable-number tandem repeats showed four genotypes among eight strains.

Abbreviations: MLVA, multilocus variable-number tandem repeat analysis; VNTR, variable-number tandem repeat.






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