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J Med Microbiol 57 (2008), 1167-1169; DOI: 10.1099/jmm.0.2008/001164-0
© 2008 Society for General Microbiology
ISSN 1473-5644

Case Report

Graft versus host disease-related Hafnia alvei colonization and probable infection

Vincenzo Savini1, Erminia Di Bartolomeo2, Chiara Catavitello1, Marzia Talia1, Assunta Manna1, Fabio Febbo1, Andrea Balbinot1, Giovanni Di Bonaventura3,4, Paolo Di Bartolomeo2, Raffaele Piccolomini3,4 and Domenico D'Antonio1

1 Clinical Microbiology and Virology Unit, Department of Transfusion Medicine, Spirito Santo Hospital, Via Fonte Romana 8, 65100 Pescara, Italy

2 Department of Hematology, Bone Marrow Transplant Centre, Spirito Santo Hospital, Pescara, Italy

3 Clinical Microbiology, Aging Research Center (Ce.S.I.), Gabriele d'Annunzio University, Chieti-Pescara, Italy

4 Department of Biomedical Sciences, Gabriele d'Annunzio University, Chieti-Pescara, Italy

Correspondence
Vincenzo Savini
vincsavi{at}yahoo.it

Received 10 February 2008
Accepted 30 April 2008

We describe the case of a graft versus host disease (GvHD) patient, in whom Hafnia alvei was cultured as a single organism, and at high bacterial counts from stool samples, from the onset of the disease until its resolution. This case is a further example of the contentious role of this species in causing human intestinal disease. Furthermore, it focuses on enteric damage by GvHD as a risk factor for acquiring H. alvei colonization, and probably infection.

Abbreviations: GvHD, graft versus host disease.






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