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J Med Microbiol 57 (2008), 534-535; DOI: 10.1099/jmm.0.47665-0
© 2008 Society for General Microbiology
ISSN 1473-5644

Case Report

Linezolid lock prophylaxis of central venous catheter infection

Jérôme Patrick Fennell1,{dagger}, Martin O'Donohoe2, Martin Cormican3 and Maureen Lynch1

1 Department of Clinical Microbiology, Mater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland

2 Department of Surgery, Mater Misericordiae University Hospital, Eccles St, Dublin 7, Ireland

3 Department of Bacteriology, National University of Ireland Galway, Galway, Ireland

Correspondence
Jérôme Patrick Fennell
Jerome.Fennell{at}amnch.ie

Received 30 September 2007
Accepted 19 December 2007

Central venous catheter (CVC)-related infections are a major problem for patients requiring long-term venous access and may result in frequent hospital admissions and difficulties in maintaining central venous access. CVC-related blood stream infections are associated with increased duration of inpatient stay and cost approximately \#8364;13 585 per patient [Blot, S. I., Depuydt, P., Annemans, L., Benoit, D., Hoste, E., De Waele, J. J., Decruyenaere, J., Vogelaers, D., Colardyn, F. & Vandewoude, K. H. (2005). Clin Infect Dis 41, 1591–1598]. Antimicrobial lock therapy may prevent CVC-related blood stream infection, preserve central venous access and reduce hospital admissions. In this paper, the impact of linezolid lock prophylaxis in a patient with short bowel syndrome is described.

Abbreviations: CNS, coagulase-negative staphylococci; CVC, central venous catheter.

{dagger}Present address: Department of Clinical Microbiology, AMNCH, Tallaght, Dublin 24, Republic of Ireland.






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