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J Med Microbiol 57 (2008), 388-391; DOI: 10.1099/jmm.0.47602-0
© 2008 Society for General Microbiology
ISSN 1473-5644

Case Report

Co-infection with two different strains of Bordetella pertussis in an infant

Pamela K. Cassiday1, Melissa Tobin-D'Angelo2, J. Renee Watson3, Kai-Hui Wu1, Mahin M. Park2 and Gary N. Sanden1

1 National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA

2 Georgia Department of Human Resources, Atlanta, GA, USA

3 Northlake Medical Center, Tucker, GA, USA

Correspondence
Pamela K. Cassiday
PCassiday{at}cdc.gov

Received 30 August 2007
Accepted 2 November 2007

We report co-infection with two phenotypically and genotypically distinct strains of Bordetella pertussis in an infant male hospitalized with a 2-week history of cough, paroxysms and vomiting. Colonies from the two B. pertussis phenotypes were isolated and evaluated by PFGE profile analysis, gene sequence typing and PCR-RFLP of a portion of the 23S rRNA gene. These results demonstrated simultaneous infection with two different strains of B. pertussis.






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