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J Med Microbiol 57 (2008), 1293-1295; DOI: 10.1099/jmm.0.2008/001883-0
© 2008 Society for General Microbiology
ISSN 1473-5644

Case Report

Successful treatment of Chromobacterium violaceum sepsis in South Africa

F. J. Bosch1, L. Badenhorst2, J. A. Le Roux2 and V. J. Louw3

1 Department of Internal Medicine, University of the Free State, Bloemfontein, South Africa

2 Department of Medical Microbiology, University of the Free State, Bloemfontein, South Africa

3 Division of Clinical Haematology, Department of Internal Medicine, University of the Free State, Bloemfontein, South Africa

Correspondence
V. J. Louw
louwvj.md{at}ufs.ac.za

Received 11 March 2008
Accepted 29 May 2008

Chromobacterium violaceum sepsis is extremely rare and usually fatal. A very few cases of C. violaceum infection have been reported from Africa, but never from South Africa. As far as could be ascertained, this infection has never been reported in a patient with leukaemia. We describe what we believe to be the first such case of C. violaceum sepsis, in a 16-year-old female patient with acute biphenotypic leukaemia, which developed during the neutropenic phase after intensive chemotherapy. The infection was due to a non-pigmented strain of C. violaceum and was associated with a co-infection with Candida parapsilosis; both were successfully treated using broad-spectrum antibiotics, antifungals and removal of a Hickman line.

Abbreviations: ALL, acute lymphoblastic leukaemia.






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