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J Med Microbiol 56 (2007), 702-705; DOI: 10.1099/jmm.0.47071-0
© 2007 Society for General Microbiology
ISSN 1473-5644

Case Report

Bacteria-associated haemophagocytic syndrome and septic pulmonary embolism caused by Burkholderia cepacia complex in a woman with chronic granulomatous disease

Michi Hisano1, Kana Sugawara1, Osamu Tatsuzawa2, Michihiro Kitagawa1, Atsuko Murashima1 and Koushi Yamaguchi1

1 Department of Perinatology, National Center for Child Health and Development, Tokyo, Japan

2 Department of Medical Specialties, Division of Infectious Disease and Rheumatology, National Center for Child Health and Development, Tokyo, Japan

Correspondence
Michi Hisano
hisano-m{at}ncchd.go.jp

Received 13 November 2006
Accepted 21 January 2007

Chronic granulomatous disease (CGD) is a primary immunodeficiency characterized by recurrent infections with certain types of bacteria and fungi. Presented herein is the case of a 29 year old woman with CGD who suffered from bacteria-associated haemophagocytic syndrome and a septic pulmonary embolism following a uterine infection and sepsis, caused by Burkholderia cepacia complex.

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BAHS, bacteria-associated haemophagocytic syndrome; BCC, Burkholderia cepacia complex; CGD, chronic granulomatous disease; CRP, C-reactive protein; CSA, cyclosporin A; CT, computed tomography; HPS, haemophagocytic syndrome; IL, interleukin; LDH, lactate dehydrogenase; PSL, prednisolone; TNF-{alpha}, tumour necrosis factor alpha; WBC, white blood cells.






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