J Med Microbiol Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nostro, A.
Right arrow Articles by Blanco, A. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nostro, A.
Right arrow Articles by Blanco, A. R.
Agricola
Right arrow Articles by Nostro, A.
Right arrow Articles by Blanco, A. R.
J Med Microbiol 56 (2007), 519-523; DOI: 10.1099/jmm.0.46804-0
© 2007 Society for General Microbiology
ISSN 1473-5644

Effects of oregano, carvacrol and thymol on Staphylococcus aureus and Staphylococcus epidermidis biofilms

Antonia Nostro1, Andrea Sudano Roccaro2, Giuseppe Bisignano1, Andreana Marino1, Maria A. Cannatelli1, Francesco C. Pizzimenti1, Pier Luigi Cioni3, Francesca Procopio1 and Anna Rita Blanco2

1 Dipartimento Farmaco-Biologico, Facoltà di Farmacia, Università degli Studi di Messina, Villaggio Annunziata, 98168 Messina, Italy

2 Direzione Ricerca, Sviluppo & Innovazione, SIFI SpA, Via Ercole Patti 36, Lavinaio, 95020 Catania, Italy

3 Dipartimento di Chimica Bioorganica e Biofarmacia, Università di Pisa, Via Bonanno 33, 56126 Pisa, Italy

Correspondence
Antonia Nostro
atnostro{at}pharma.unime.it

Received 27 June 2006
Accepted 18 December 2006

The aim of this study was to evaluate the effect of oregano essential oil, carvacrol and thymol on biofilm-grown Staphylococcus aureus and Staphylococcus epidermidis strains, as well as the effects of the oils on biofilm formation. For most of the S. aureus (n=6) and S. epidermidis (n=6) strains tested, the biofilm inhibitory concentration (0.125–0.500 %, v/v, for oregano, and 0.031–0.125 %, v/v, for carvacrol and thymol) and biofilm eradication concentration (0.25–1.0 %, v/v, for oregano and 0.125–0.500 %, v/v, for carvacrol and thymol) values were twofold or fourfold greater than the concentration required to inhibit planktonic growth. Subinhibitory concentrations of the oils attenuated biofilm formation of S. aureus and S. epidermidis strains on polystyrene microtitre plates.

Abbreviations: BEC, biofilm eradication concentration; BIC, biofilm inhibitory concentration; MBC, minimum bactericidal concentration.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL J MED MICROBIOL MICROBIOLOGY J GEN VIROL ALL SGM JOURNALS
Copyright © 2007 Society for General Microbiology.