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J Med Microbiol 55 (2006), 1601-1603; DOI: 10.1099/jmm.0.46614-0
© 2006 Society for General Microbiology
ISSN 1473-5644

Case Report

Molecular evidence for vertical transmission of listeriosis, Taiwan

Yu-Tsung Huang1, Shee-Uan Chen2, Mu-Zon Wu2, Chien-Yir Chen2, Wuu-Shiun Hsieh2, Buor-Niarn Tsao2, Chieh Jou Horng2 and Po-Ren Hsueh2,3

1 Department of Internal Medicine, Far Eastern Memorial Hospital, Taiwan

2 ,3 Department of Internal Medicine2 and Department of Laboratory Medicine3 , National Taiwan University Hospital, National Taiwan University College of Medicine, Taiwan

Correspondence
Po-Ren Hsueh
hsporen{at}ha.mc.ntu.edu.tw

Received 8 March 2006
Accepted 1 August 2006

The case is presented of a pregnant woman at the 31st week of gestation with Listeria monocytogenes bacteraemia and microabscess formation in the endometrium, who delivered an infant with disseminated infection (meningitis and bacteraemia). The two patients were successfully treated with intravenous ampicillin and gentamicin. Molecular typing using random amplified polymorphic DNA (RAPD) analysis disclosed that three isolates from the mother (blood) and infant (blood and cerebrospinal fluid) had identical RAPD profiles.

Abbreviations: CSF, cerebrospinal fluid; ICU, intensive care unit; RAPD, random amplified polymorphic DNA; WBC, white blood cell.




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