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J Med Microbiol 55 (2006), 1329-1331; DOI: 10.1099/jmm.0.46667-0
© 2006 Society for General Microbiology
ISSN 1473-5644

IgG and IgG subclass antibodies in patients with active cutaneous leishmaniasis

Hatice Ozbilge1, Nurten Aksoy2, Mehmet S. Gurel3 and Suleyman Yazar4

1 ,4 Department of Pharmaceutical Microbiology1 and Faculty of Pharmacy and Parasitology4 , Faculty of Medicine, Erciyes University, Kayseri, Turkey

2 ,3 Departments of Biochemistry2 and Dermatology3 , Harran University Medical Faculty, Sanliurfa, Turkey

Correspondence
Suleyman Yazar
syazar{at}erciyes.edu.tr

Received 7 April 2006
Accepted 9 May 2006

This research was planned to detect IgG and IgG subclasses in sera of patients with active cutaneous leishmaniasis (CL). Sera from 30 patients with active CL aged between 10 and 50 years and from 30 healthy controls aged between 8 and 50 years were included in the study. Levels of IgG and its subclasses were measured by a nephelometer. Levels of IgG, IgG1 and IgG3 in the CL patients were higher than in the controls. In addition, IgG and IgG1, and IgG and IgG3 levels showed a significant positive correlation. These results showed that IgG subclasses could possibly be used as a helpful diagnostic marker in CL.

Abbreviations: CL, cutaneous leishmaniasis; VL, visceral leishmaniasis.






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