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J Med Microbiol 55 (2006), 89-92; DOI: 10.1099/jmm.0.46255-0
© 2006 Society for General Microbiology
ISSN 0022-2615

Anti-Toxoplasma gondii antibodies in patients with chronic heart failure

Süleyman Yazar1, Mustafa Gur2,{dagger}, Ibrahim Ozdogru2, Ozan Yaman1, Abdurrahman Oguzhan2 and Izzet Sahin1

Departments of Parasitology1 and Cardiology2 , Medical Faculty, Erciyes University, 38039-Kayseri, Turkey

Correspondence
Süleyman Yazar
syazar{at}erciyes.edu.tr

Received 19 July 2005
Accepted 31 August 2005

Chronic heart failure (CHF) involves interactions between the cardiovascular, neuroendocrine and immune systems. This study investigated the seropositivity rate for anti-Toxoplasma IgG and IgM antibodies by ELISA in patients with CHF. Ninety-seven patients with CHF and 50 healthy volunteers were selected for this investigation. The seropositivity rate for anti-Toxoplasma IgG antibodies among CHF patients (68 %) was significantly higher than in healthy volunteers (36 %). Thus, parasitological screening of this group of patients should be periodically performed to prevent the possible dissemination of toxoplasmosis.

Abbreviations: CHF, chronic heart failure; IL, interleukin; IFN, interferon; NK, natural killer.

{dagger}Present address: Harran University, Medical Faculty, Department of Cardiology, Sanliurfa, Turkey.






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