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J Med Microbiol 54 (2005), 685-688; DOI: 10.1099/jmm.0.46016-0
© 2005 Society for General Microbiology
ISSN 0022-2615

Fatal pulmonary infection in a leukaemic patient caused by Hormographiella aspergillata

Katrien Lagrou1, Caroline Massonet1, Koen Theunissen2, Wouter Meersseman3, Marc Lontie4, Eric Verbeken5, Johan Van Eldere1 and Johan Maertens2

1,2,3,5Immunology and Microbiology1, Hematology2, Internal Medicine3 and Pathology5, University Hospital Leuven, Herestraat 49, 3000 Leuven, Belgium 4Laboratory for Microbiology, MCH, Maria Theresiastraat 63A, 3000 Leuven, Belgium

Correspondence Katrien Lagrou katrien.lagrou{at}uz.kuleuven.ac.be

Received January 18, 2005
Accepted March 16, 2005

A case of autopsy-proven fungal pneumonia in a relapsed leukaemia patient is reported. The fungus Hormographiella aspergillata was cultured from two bronchoalveolar fluid samples and identified through morphological examination and ITS2 sequence analysis. In addition, galactomannan was detected in eight consecutive serum samples, which suggested a co-infection with Aspergillus species. The patient was treated with caspofungin.

Abbreviations: BAL, bronchoalveolar fluid; ITS2, internal transcribed spacer 2.






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