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Clostridium fallax associated with sudden death in a 16-year-old boy

^1,2Institute of Legal Medicine¹ and Institute of Clinical Microbiology, Immunology and Hygiene², University of Erlangen-Nürnberg, Germany

Correspondence Roland Hausmann roland.hausmann{at}recht.imed.uni-erlangen.de

Received October 6, 2003
Accepted February 4, 2004

Clostridial myonecrosis or gas gangrene occurs most frequently in contaminated wounds following trauma or surgery. It is caused by a wide variety of Clostridium species, the most common being Clostridium perfringens. Spontaneous, non-traumatic clostridial myonecrosis is uncommon and is usually associated with gastrointestinal and haematological malignancy, diabetes mellitus and peripheral vascular disease. The case of a previously healthy 16-year-old boy with acute onset of gastrointestinal symptoms, who died of bacterial sepsis without apparent preceding trauma, is presented here. Clostridium fallax was identified as the most probable causative agent. As far as is known, this is the first report of fatal sepsis in humans due to C. fallax, which has been described only rarely as a cause of gas oedema in animals.

The GenBank/EMBL/DDBJ accession number for the sequence reported in this paper is AY208919.