J Med Microbiol Track the topics, authors and articles important to you
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sugunan, A P
Right arrow Articles by Sehgal, S C
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sugunan, A P
Right arrow Articles by Sehgal, S C
Agricola
Right arrow Articles by Sugunan, A P
Right arrow Articles by Sehgal, S C
J Med Microbiol 53 (2004), 1259-1262; DOI: 10.1099/jmm.0.45735-0
© 2004 Society for General Microbiology
ISSN 0022-2615

Percutaneous exposure resulting in laboratory-acquired leptospirosis – a case report

A P Sugunan, K Natarajaseenivasan, P Vijayachari and S C Sehgal

WHO Collaborative Centre for Diagnosis, Research, Reference and Training in Leptospirosis, Regional Medical Research Centre, Indian Council of Medical Research, Post Bag No. 13, Port Blair 744 101, Andaman & Nicobar Islands, India

Correspondence S. C. Sehgal pblicmr{at}sancharnet.in

Received May 7, 2004
Accepted August 4, 2004

A screw-capped glass tube containing a Leptospira culture accidentally broke and the laboratory worker who was handling the tube sustained a cut on his hand. The wound was flooded with the culture. The culture was that of strain MG 347 belonging to serovar Australis recovered from a patient, and it had undergone 52 passages in Ellinghausen McCullough Johnson Harris medium. The laboratory worker developed a headache 21 days after the accident and became febrile the next day. He was hospitalized for 5 days and was treated initially with doxycycline and later with ciprofloxacin. A blood sample collected on the second day of illness, after starting doxycycline therapy, yielded leptospires and the isolate, HZ 651, was identified as serovar Australis. Monoclonal antibody patterns and randomly amplified polymorphic DNA fingerprinting patterns of the isolate and strain MG 347 were identical, thus indicating that HZ 651 and MG 347 were clonal.

Abbreviations: MAT, microscopic agglutination test; RAPD, randomly amplified polymorphic DNA.




This article has been cited by other articles:


Home page
 J Med MicrobiolHome page
A. M Bal
Use of ciprofloxacin for treating leptospirosis - need for clinical trials
J. Med. Microbiol., September 1, 2005; 54(9): 907 - 907.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL J MED MICROBIOL MICROBIOLOGY J GEN VIROL ALL SGM JOURNALS
Copyright © 2004 Society for General Microbiology.