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J Med Microbiol 53 (2004), 1183-1186; DOI: 10.1099/jmm.0.45587-0
© 2004 Society for General Microbiology
ISSN 0022-2615

Investigation of anti-Toxoplasma gondii antibodies in patients with neoplasia

Süleyman Yazar1, Ozan Yaman1, Bülent Eser2, Fevzi Altuntas2, Fatih Kurnaz2 and Izzet Sahin1

Departments of Parasitology1 and Haematology2, Erciyes University Medical Faculty, 38039 Kayseri, Turkey

Correspondence Süleyman Yazar syazar{at}erciyes.edu.tr

Received January 9, 2004
Accepted August 10, 2004

This study aimed to determine the prevalence of anti-Toxoplasma gondii antibodies in patients with neoplasia. One hundred and eight patients with neoplasia and 108 healthy controls were studied for the presence of anti-T. gondii antibodies using a micro ELISA and peroxidase-labelled anti-human IgG (rabbit) and IgM (goat). Anti-T. gondii IgG antibodies were detected in 68 (63.0 %) patients and in 21 (19.4 %) of the controls, which was a statistically significant difference. In addition, anti- T. gondii IgM antibodies were detected in seven (6.5 %) patients and in one (0.9 %) control. A high percentage of positivity for Toxoplasma antibodies in patients with neoplasia was detected. Therefore, parasitological surveys of this patient group should be periodically performed.






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