J Med Microbiol NEW Faster Access
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Bruun, B.
Right arrow Articles by Kilian, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bruun, B.
Right arrow Articles by Kilian, M.
Agricola
Right arrow Articles by Bruun, B.
Right arrow Articles by Kilian, M.
J Med Microbiol 53 (2004), 1161-1165; DOI: 10.1099/jmm.0.45749-0
© 2004 Society for General Microbiology
ISSN 0022-2615

Clonal relationship of recent invasive Haemophilus influenzae serotype f isolates from Denmark and the United States

Brita Bruun1,2, Bente Gahrn-Hansen3, Henrik Westh4 and Mogens Kilian5

1Department of Clinical Microbiology, Statens Serum Institut, Artillerivej 5, DK 2300 Copenhagen S, Denmark 2Department of Clinical Microbiology, Hillerød Hospital, Helsevej 2, DK 3400 Hillerød, Denmark 3Department of Clinical Microbiology, Odense University Hospital, J. B. Winsløvsvej 21.2, DK 5000 Odense C, Denmark 4Department of Clinical Microbiology, Hvidovre Hospital, Kettegaard Alle 30, DK 2650 Hvidovre, Denmark 5Department of Medical Microbiology and Immunology, Århus University, Universitetsparken, DK 8000 Århus C, Denmark

Correspondence Bente Gahrn-Hansen b.gahrn-hansen{at}ouh.fyns-amt.dk

Received May 18, 2004
Accepted July 29, 2004

Surveillance performed after the introduction of general Haemophilus influenzae serotype b (Hib) vaccination in Denmark identified 13 cases of invasive bacteraemic H. influenzae serotype f (Hif) disease in adults over a period of 7 years. Bacteraemic respiratory tract infections accounted for 61 % of cases, but meningitis, epiglottitis and osteoarthritis were also seen. Recent Danish isolates were compared to recent American isolates, historical Hif strains and non-Hif invasive strains. Results of conventional serotyping were confirmed by PCR detection of the serotype-f-specific cap and bexA gene sequences. Multilocus enzyme electrophoresis typing revealed that recent Danish and American isolates belonged to a single Hif clone, which may be undergoing expansion. The need for accurate serotyping of H. influenzae to enable reliable monitoring for Hib replacement by other capsular types is emphasized.

Abbreviations: COPD, chronic obstructive pulmonary disease; CSF, cerebrospinal fluid; Hib, Haemophilus influenzae serotype b; Hif, H. influenzae serotype f; MLEE, multilocus enzyme electrophoresis.




This article has been cited by other articles:


Home page
 J Med MicrobiolHome page
E. McLellan, K. Suvarna, and R. Townsend
Fatal necrotizing fasciitis caused by Haemophilus influenzae serotype f
J. Med. Microbiol., February 1, 2008; 57(2): 249 - 251.
[Abstract] [Full Text] [PDF]

Home page
 J. Immunol.Home page
M. Samuelsson, T. Hallstrom, A. Forsgren, and K. Riesbeck
Characterization of the IgD Binding Site of Encapsulated Haemophilus influenzae Serotype b
J. Immunol., May 15, 2007; 178(10): 6316 - 6319.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL J MED MICROBIOL MICROBIOLOGY J GEN VIROL ALL SGM JOURNALS
Copyright © 2004 Society for General Microbiology.