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MOLECULAR EPIDEMIOLOGY |
Medical Microbiology, Ninewells Hospital and Medical School, Dundee DD1 9SY and *Scottish Salmonella Reference Laboratory, Stobhill Hospital, Glasgow G21 3UW
Corresponding author: Dr D.C. Old (e-mail: davido{at}tuht.scot.nhs.uk).
Received 29 Sept. 2000; accepted 8 Nov. 2000.
Abstract
The isolation since 1991 of a new serotype of Salmonella enterica (antigenic formula 4,12:a:-) from harbour porpoises (Phocoena phocoena) at post-mortem examination raised the question of its evolutionary origin. Representative strains of S. enterica serotype 4,12:a:- and strains of eight other serotypes of serogroup O4 with phase-1 flagellar antigen H a were examined by EcoRI ribotyping, IS200 fingerprinting and PCR-based profiling. Statistical analysis of results of multiple typing showed that strains of Salmonella serotype 4,12:a:- were genetically distant from those of antigenically similar salmonella serotypes, none of which seemed likely to be the progenitor of the porpoise serotype.
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