J Med Microbiol Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Blackwood, R. A.
Right arrow Articles by Bloch, C. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Blackwood, R. A.
Right arrow Articles by Bloch, C. A.
Agricola
Right arrow Articles by Blackwood, R. A.
Right arrow Articles by Bloch, C. A.

The Journal of Medical Microbiology, Vol 46, Issue 6 506-510, Copyright © 1997 by Society for General Microbiology

JOURNAL ARTICLE

Pulsed-field gel electrophoresis genomic fingerprinting of hospital Escherichia coli bacteraemia isolates

R. A. Blackwood, C. K. Rode, C. L. Pierson and C. A. Bloch
Department of Pediatrics, University of Michigan, Ann Arbor 48109-0244, USA.

Pulsed-field gel electrophoresis (PFGE), because of the increased sensitivity it affords over other methods of bacterial genotyping, represents a potentially powerful tool for the characterisation of isolates from hospital infections. Genomic fingerprinting by PFGE was applied to all clinical isolates of Escherichia coli obtained from blood during a 6-month period (78 isolates, 58 patients) at the University of Michigan Medical Center. The rare-restriction patterns of these isolates, in contrast to those of isolates from the E. coli reference collection (ECOR), were not randomly distributed through the E. coli species. Four related clusters, which represented c. 21% of the blood isolates, were identified. Two of these genotypic clusters were also clustered temporally, their members all being isolated within the same 2-week period, while the other two clusters spanned the study period. These observations indicate in-hospital endemic vectors or the occurrence of specialised E. coli lineages that are capable of invading the bloodstream and exploiting in-hospital vectors, or both.


This article has been cited by other articles:


Home page
 Antimicrob. Agents Chemother.Home page
S. Y. Essack, L. M. C. Hall, D. G. Pillay, M. L. McFadyen, and D. M. Livermore
Complexity and Diversity of Klebsiella pneumoniae Strains with Extended-Spectrum {beta}-Lactamases Isolated in 1994 and 1996 at a Teaching Hospital in Durban, South Africa
Antimicrob. Agents Chemother., January 1, 2001; 45(1): 88 - 95.
[Abstract] [Full Text]

Home page
 Infect. Immun.Home page
L. J. Melkerson-Watson, C. K. Rode, L. Zhang, B. Foxman, and C. A. Bloch
Integrated Genomic Map from Uropathogenic Escherichia coli J96
Infect. Immun., October 1, 2000; 68(10): 5933 - 5942.
[Abstract] [Full Text] [PDF]

Home page
 J. Bacteriol.Home page
A. Wada, R. Mikkola, C. G. Kurland, and A. Ishihama
Growth Phase-Coupled Changes of the Ribosome Profile in Natural Isolates and Laboratory Strains of Escherichia coli
J. Bacteriol., May 15, 2000; 182(10): 2893 - 2899.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL J MED MICROBIOL MICROBIOLOGY J GEN VIROL ALL SGM JOURNALS
Copyright © 1997 Society for General Microbiology.