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The Journal of Medical Microbiology, Vol 44, Issue 1 60-64, Copyright © 1996 by Society for General Microbiology

JOURNAL ARTICLE

Characterisation of an enterotoxin-negative, cytotoxin-positive strain of Clostridium sordellii

G. A. Green, V. Schue, R. Girardot and H. Monteil
Laboratoire de Toxinologie Bacterienne, Faculte de Medecine, Universite Louis Pasteur, Strasbourg, France.

In ileal loop assay, ELISA and anion-exchange column chromatography, Clostridium sordellii strain 6018 was shown to produce a cytotoxin, but no detectable enterotoxin. DNA sequence and polymerase chain reaction analyses indicated that the lack of enterotoxin activity is not due to a lack of gene transcription, but to lack of a major portion of the enterotoxin gene. This is the first characterisation of such a strain.


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[Abstract] [Full Text]


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