J Med Microbiol Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Med Microbiol 4 (1971), 51-61; DOI: 10.1099/00222615-4-1-51
© 1971 Society for General Microbiology
ISSN 0022-2615
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Iida, T.
Right arrow Articles by Okonogi, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Iida, T.
Right arrow Articles by Okonogi, T.
Agricola
Right arrow Articles by Iida, T.
Right arrow Articles by Okonogi, T.

Lienotoxicity Of Bordetella Pertussis In Mice

T. Iida1 and T. Okonogi1

Central Research Laboratories, Sankyo Co. Ltd, Hiromachi, Shinagawa-ku, Tokyo

Received April 3, 1970
Accepted June 9, 1970

A highly toxic fraction causing dermonecrosis in guinea-pigs and a lethal effect in mice was obtained from Bordetella pertussis phase-1 organisms. Intravenous injection of this toxic fraction into mice produced a considerable reduction in spleen weight within 7 days. The histological findings indicate that B. pertussis causes an atrophy of the spleen. The term "lienotoxicity" is proposed to designate this toxic phenomenon. Whether dermonecrosis, lethality and lienotoxicity are caused by three different agents contained in the preparation studied has not been determined.




This article has been cited by other articles:


Home page
 Clin. Microbiol. Rev.Home page
S. Mattoo and J. D. Cherry
Molecular Pathogenesis, Epidemiology, and Clinical Manifestations of Respiratory Infections Due to Bordetella pertussis and Other Bordetella Subspecies
Clin. Microbiol. Rev., April 1, 2005; 18(2): 326 - 382.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
T. Matsuzawa, T. Kashimoto, J. Katahira, and Y. Horiguchi
Identification of a Receptor-Binding Domain of Bordetella Dermonecrotic Toxin
Infect. Immun., July 1, 2002; 70(7): 3427 - 3432.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
T. Kashimoto, J. Katahira, W. R. Cornejo, M. Masuda, A. Fukuoh, T. Matsuzawa, T. Ohnishi, and Y. Horiguchi
Identification of Functional Domains of Bordetella Dermonecrotizing Toxin
Infect. Immun., August 1, 1999; 67(8): 3727 - 3732.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
Y. Horiguchi, N. Inoue, M. Masuda, T. Kashimoto, J. Katahira, N. Sugimoto, and M. Matsuda
Bordetella bronchiseptica dermonecrotizing toxin induces reorganization of actin stress fibers through deamidation of Gln-63 of the GTP-binding protein Rho
PNAS, October 14, 1997; 94(21): 11623 - 11626.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
Y Horiguchi, T Senda, N Sugimoto, J Katahira, and M Matsuda
Bordetella bronchiseptica dermonecrotizing toxin stimulates assembly of actin stress fibers and focal adhesions by modifying the small GTP-binding protein rho
J. Cell Sci., January 10, 1995; 108(10): 3243 - 3251.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL J MED MICROBIOL MICROBIOLOGY J GEN VIROL ALL SGM JOURNALS
Copyright © 1971 Society for General Microbiology.