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The Journal of Medical Microbiology, Vol 36, Issue 1 52-55, Copyright © 1992 by Society for General Microbiology


JOURNAL ARTICLE

Aggregation of human granulocytes by Staphylococcus aureus lipase

J. Rollof, E. Vinge, P. Nilsson-Ehle and J. H. Braconier
Department of Infectious Diseases, University Hospital of Lund, Sweden.

The effects of purified extracellular lipase from Staphylococcus aureus on human granulocytes were studied in vitro with a turbidimetric technique. Within the concentration range 0.6-4.4 micrograms/ml, lipase caused monophasic aggregation accompanied by the release of lactoferrin; the corresponding concentrations of the solvent in which it was suspended, Triton X100, had no effect. Lipase-induced aggregation did not occur in the presence of autologous plasma.





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