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The Journal of Medical Microbiology, Vol 35, Issue 4 244-248, Copyright © 1991 by Society for General Microbiology

JOURNAL ARTICLE

Serological diagnosis with the Chlamydia Spot-IF test

P. T. Mannion, H. Mallinson and J. D. Treharne
Liverpool Public Health Laboratory, Fazakerley Hospital.

Using a set of sera for which full chlamydial micro-immunofluorescence results suggested a clear diagnosis, we have evaluated the Chlamydia Spot-IF test (bioMerieux), which allows a comparison of titres to Chlamydia trachomatis and C. psittaci antigens. A modification of the test in which the antigen slides were pre-treated with a monoclonal antibody to chlamydial lipopolysaccharide, improved its ability to differentiate infections with C. trachomatis from those with C. psittaci or C. pneumoniae.


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