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The Journal of Medical Microbiology, Vol 35, Issue 2 93-97, Copyright © 1991 by Society for General Microbiology

JOURNAL ARTICLE

Adherence of Serratia marcescens in the pathogenesis of urinary tract infections in diabetic mice

Y. Obana, K. Shibata and T. Nishino
Department of Microbiology, Kyoto Pharmaceutical University, Japan.

The adherence of Serratia marcescens to bladder epithelial cells of mice with alloxan-induced diabetes was studied. S. marcescens adhered more strongly to the bladder epithelial cells of diabetic mice than to those of normal mice both in vitro and in vivo. The susceptibility of diabetic mice to urinary tract infection may be due to an increased adhesive capacity of bladder epithelial cells.


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M. D. Mastropaolo, N. P. Evans, M. K. Byrnes, A. M. Stevens, J. L. Robertson, and S. B. Melville
Synergy in Polymicrobial Infections in a Mouse Model of Type 2 Diabetes
Infect. Immun., September 1, 2005; 73(9): 6055 - 6063.
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