J Med Microbiol Track the topics, authors and articles important to you
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hellyer, T. J.
Right arrow Articles by Easmon, C. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hellyer, T. J.
Right arrow Articles by Easmon, C. S.
Agricola
Right arrow Articles by Hellyer, T. J.
Right arrow Articles by Easmon, C. S.

The Journal of Medical Microbiology, Vol 34, Issue 4 225-231, Copyright © 1991 by Society for General Microbiology

JOURNAL ARTICLE

Plasmid analysis of Mycobacterium avium-intracellulare (MAI) isolated in the United Kingdom from patients with and without AIDS

T. J. Hellyer, I. N. Brown, J. W. Dale and C. S. Easmon
Department of Medical Microbiology, St Mary's Hospital Medical School, London.

One hundred and forty-seven isolates (128 strains) of Mycobacterium avium-intracellulare (MAI) were screened by agarose gel electrophoresis for the presence of plasmids. Plasmids were characterised according to size and by Southern hybridisation analysis of intact and restriction endonuclease-digested DNA. Two cloned MAI plasmids, pLR7 and pLR20, were used as probes. There was no significant difference in the rate of plasmid carriage in MAI strains isolated from patients with the acquired immuno-deficiency syndrome (AIDS) and from non-AIDS patients in the UK, but a higher rate of plasmid carriage was observed in a panel of American strains from AIDS patients. Plasmids were grouped into two broad categories: small (mostly 14-30 kb) and large (greater than 150 kb). Southern blot analysis identified two distinct groups of small plasmids, the majority of which showed homology with pLR7. Plasmids from this group were significantly more common in strains of serotypes 4 and 8 which are particularly associated with AIDS.


This article has been cited by other articles:


Home page
 Clin. Microbiol. Rev.Home page
C. Y. Turenne, R. Wallace Jr., and M. A. Behr
Mycobacterium avium in the Postgenomic Era
Clin. Microbiol. Rev., April 1, 2007; 20(2): 205 - 229.
[Abstract] [Full Text] [PDF]

Home page
 MicrobiologyHome page
E. Krzywinska, J. Krzywinski, and J. S. Schorey
Naturally occurring horizontal gene transfer and homologous recombination in Mycobacterium
Microbiology, June 1, 2004; 150(6): 1707 - 1712.
[Abstract] [Full Text] [PDF]

Home page
 Infect. Immun.Home page
K. A. Birkness, W. E. Swords, P.-H. Huang, E. H. White, C. S. Dezzutti, R. B. Lal, and F. D. Quinn
Observed Differences in Virulence-Associated Phenotypes between a Human Clinical Isolate and a Veterinary Isolate of Mycobacterium avium
Infect. Immun., September 1, 1999; 67(9): 4895 - 4901.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL J MED MICROBIOL MICROBIOLOGY J GEN VIROL ALL SGM JOURNALS
Copyright © 1991 Society for General Microbiology.