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The Journal of Medical Microbiology, Vol 31, Issue 2 103-108, Copyright © 1990 by Society for General Microbiology

JOURNAL ARTICLE

Pathogenic potential of Eubacterium yurii subspecies

B. S. Margaret, J. R. Heath and G. N. Krywolap
Department of Microbiology, University of Maryland Dental School, Baltimore.

Several mechanisms that could contribute to the periodontopathogenic potential of Eubacterium yurii were investigated. All 18 strains examined produced RNAase and the metabolites H2S, indole and butyrate. Some strains produced phosphatase and DNAase. Methanol extracts of whole cells of E. yurii subspp. yurii and margaretiae stimulated bone resorption in vitro comparable to that produced by recognised periodontal pathogens. These results suggest that further studies should be performed to elucidate the role of E. yurii in periodontal disease.




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