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The Journal of Medical Microbiology, Vol 28, Issue 2 109-112, Copyright © 1989 by Society for General Microbiology

JOURNAL ARTICLE

Age-dependent changes in protease and elastase production in cultures of Pseudomonas aeruginosa

S. Umeki
Department of Medicine, Kawasaki Medical School, Okayama, Japan.

The intracellular and extracellular protease and elastase contents of Pseudomonas aeruginosa were studied in relation to the age of the culture. The intracellular protease and elastase content of the organisms decreased as the culture grew older, whereas extracellular protease and elastase greatly increased 24 h after incubation commenced, suggesting that host tissue injury by P. aeruginosa infection may increase in proportion to the duration of tissue colonisation.




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