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The Journal of Medical Microbiology, Vol 26, Issue 3 237-239, Copyright © 1988 by Society for General Microbiology

JOURNAL ARTICLE

A study of the evolution of specific and non-specific immune complexes in acute hepatitis B and chronic hepatitis

A. Leyva, M. C. Bernal, G. Piedrola and M. C. Maroto
Department of Microbiology, School of Medicine, Granada, Spain.

Circulating immune complexes (ICs) containing IgG and HBsAg, and IgG and HBeAg, in sera from groups of patients with various liver diseases were sought by ELISA and immunodiffusion. A correlation was found between the absence of ICs and the disappearance of HBsAg in patients who had recovered from acute hepatitis B, but complexes containing HBsAg were always found in chronic hepatitis.




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