The Journal of Medical Microbiology, Vol 25, Issue 2 151-153, Copyright © 1988 by Society for General Microbiology

JOURNAL ARTICLE

The prevalence of antibody to human parvovirus B19 in England and Wales

B. J. Cohen and M. M. Buckley
Virus Reference Laboratory, Central Public Health Laboratory, London.

The prevalence of antibody to human parvovirus B19 (anti-B19 IgG) in England and Wales was measured by an antibody-capture radioimmunoassay. Over 2000 sera were examined; 1422 from the general population, 374 from unselected children admitted to hospital and 300 from women attending an antenatal clinic. Waning levels of maternally-derived antibody were found in infants under 1 year old. In children 1-5 years old, 5-15% had anti-B19 IgG and this rose to 50-60% in older children, young adults and women of child-bearing age. In older people, the prevalence of anti-B19 IgG increased with age, rising to more than 85% in those over 70 years old.

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