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The Journal of Medical Microbiology, Vol 24, Issue 3 227-232, Copyright © 1987 by Society for General Microbiology

JOURNAL ARTICLE

R-plasmid RP1 promotes adhesion of gram-negative bacteria to medical prostheses and glass

J. A. Onaolapo, M. I. el-Haffar, D. Townley and R. M. Klemperer
Department of Pharmaceutical Sciences, Aston University, Birmingham.

The presence of R-plasmid RP1 increased the adhesion of chemostat-grown iron- and carbon-limited Proteus mirabilis to the surfaces of various medical prostheses and to glass. Similar results were obtained with iron-limited Pseudomonas aeruginosa and anaerobically-grown Escherichia coli. Changes in the surface properties of P. mirabilis indicated that the R-plasmid-mediated increase in negative charge was one of the factors that promoted adhesion.




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