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The Journal of Medical Microbiology, Vol 17, Issue 3 247-257, Copyright © 1984 by Society for General Microbiology

JOURNAL ARTICLE

Phagocytic and serum killing of capsulate and non-capsulate Bacteroides fragilis

J. H. Reid and S. Patrick

The relative susceptibilities of capsulate and non- capsulate variants of Bacteroides fragilis to serum and phagocytic killing were investigated. The capsule of B. fragilis did not confer resistance to serum killing. Phagocytic killing of non- capsulate B. fragilis occurred at bacterial concentrations of 1 X 10(6) and 1 X 10(7) cfu/ml. Capsulate B. fragilis organisms were also phagocytosed and killed at a concentration of 1 X 10(6) cfu/ml, but phagocytosis and killing were impaired at a concentration of 1 X 10(7) cfu/ml.


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