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The Journal of Medical Microbiology, Vol 15, Issue 2 253-258, Copyright © 1982 by Society for General Microbiology

JOURNAL ARTICLE

Cytotoxic activity of Bacteroides gingivalis and Bacteroides asaccharolyticus

T. J. van Steenbergen, M. D. dan Ouden, J. J. Touw and J. de Graaff

Culture filtrates of all eight strains of Bacteroides gingivalis and all five strains of B. asaccharolyticus were toxic for Vero cells. Cytotoxicity was in general greater with material from cultures of B. gingivalis than from B. asaccharolyticus but none of the culture filtrates from eight strains of B. melaninogenicus showed activity in this test. The toxic material was released during prolonged incubation and more detailed study of preparations from one strain indicated that it had a molecular weight of less than 3500 and was heat stable.




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