J Med Microbiol NEW Faster Access
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Taniguchi, K.
Right arrow Articles by Urasawa, T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Taniguchi, K.
Right arrow Articles by Urasawa, T.
Agricola
Right arrow Articles by Taniguchi, K.
Right arrow Articles by Urasawa, T.

The Journal of Medical Microbiology, Vol 14, Issue 1 107-118, Copyright © 1981 by Society for General Microbiology

JOURNAL ARTICLE

Further studies of 35--40 nm virus-like particles associated with outbreaks of acute gastroenteritis

K. Taniguchi, S. Urasawa and T. Urasawa

Virus-like particles similar in size and morphology to the Otofuke agent, which was detected first in an institutional outbreak of acute gastroenteritis at Otofuke, Hokkaido, Japan in 1978, were again observed in faeces from patients in four other outbreaks of acute gastroenteritis in Hokkaido. In each of three outbreaks in which the faeces and paired sera of patients were available, apparent sero-responses against the particles obtained in corresponding outbreaks were confirmed. Serological analysis of the particles from five separate epidemics by immune electronmicroscopy suggested that the particles from these epidemics may be related antigenically to one another. Besides the above-mentioned particles measuring 35--40 nm in diameter, 15--20-nm "empty" particles were also found in the stool specimens obtained from two of the five epidemics. In addition, serological cross reactivity between these two kinds of particles was observed. These findings provide further support for the aetiological role of the 35--40-nm particles (Otofuke agent-like particles) in acute gastroenteritis in older children and adults.




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL J MED MICROBIOL MICROBIOLOGY J GEN VIROL ALL SGM JOURNALS
Copyright © 1981 Society for General Microbiology.