The Journal of Medical Microbiology, Vol 13, Issue 3 383-391, Copyright © 1980 by Society for General Microbiology
Resistance to cadmium, arsenate and mercury among Danish strains of Staphylococcus aureus isolated from cases of bacteriaemia, 1957-74
V. T. Rosdahl and K. Rosendal
A collection of 3040 epidemiologically-unrelated strains of Staphylococcus
aureus isolated from blood cultures during the period 1957-74 was examined
for their resistance to cadmium (Cd), arsenate (As) and mercury (Hg); 98%
of the strains had metal-resistance patterns of (a) sensitive to all these
metals, (b) resistant to Cd, (c) resistant to Cd,As or (d) resistant to
Cd,As,Hg. The percentage of Cd,As,Hg-resistant strains fell from 50 to 13
in the period of investigation and the percentage of Cd-resistant strains
increased from 11 to 32. Strains resistant only to Cd were mainly P
resistant only and a correlation was found between multiple antibiotic
resistance and Cd,As,Hg resistance. Strains of phage types 80/81,
52/52A/80/81 and 52/52A/80 were never Cd resistant only, but mainly
Cd,As,Hg resistant. Strains of the 94, 96 complex were mainly Cd resistant
and were never resistant to Cd,As,Hg.
