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The Journal of Medical Microbiology, Vol 11, Issue 1 7-14, Copyright © 1978 by Society for General Microbiology
JOURNAL ARTICLE |
M. Edwards and J. M. Stark
Three capsulate pneumococcal strains of serotypes 1, 2 ans 3, and one non-capsulate strain of serotype 47, were found to activate human complement by the alternative pathway to a similar extent over the concentration range examined. Nevertheless, the capsulate strains, in contrast to the non-capsulate, are known to require complement attachment for phagocytosis and it is therefore postulated that the toxic by-products released cause the wave of oedema characteristic of pneumococcal lobar pneumonia.
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