J Med Microbiol Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via CrossRef
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Watanakunakorn, C.
Right arrow Articles by Glotzbecker, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Watanakunakorn, C.
Right arrow Articles by Glotzbecker, C.
Agricola
Right arrow Articles by Watanakunakorn, C.
Right arrow Articles by Glotzbecker, C.

The Journal of Medical Microbiology, Vol 10, Issue 1 133-138, Copyright © 1977 by Society for General Microbiology

JOURNAL ARTICLE

Synergism with aminoglycosides of penicillin, ampicillin and vancomycin against non-enterococcal group-D streptococci and viridans streptococci

C. Watanakunakorn and C. Glotzbecker

The antibiotic susceptibility of 10 strains of non-enterococcal group-D streptococci was compared with that of 20 strains of viridans streptococci. The minimal inhibitory concentrations of penicillin, ampicillin, oxacillin, nafcillin, cephalothin, vancomycin, erythromycin and clindamycin for the two groups of streptococci were very similar in range and median values. Both groups of streptococci were resistant to the aminoglycosides. The effect of the combination of penicillin, ampicillin or vancomycin with streptomycin, kanamycin, gentamicin or tobramycin on the in-vitro killing of the two groups of streptococci was compared. For all the antibiotic combinations tested, synergism was demonstrated against all strains of non-enterococcal group-D streptococci after one or more of the time-intervals 6, 24 and 48 h. Some or all of the antibiotic combinations were synergistic against all strains of viridans streptococci after one or more of the same time-intervals. The other aminoglycosides (kanamycin, gentamicin and tobramycin) offered no advantage over streptomycin in synergism with penicillin, ampicillin or vancomycin against nonenterococcal group-D streptococci or viridans streptococci. These results suggest that non-enterococcal group-D streptococcal endocarditis may be treated by the same regimen as endocarditis caused by the viridans streptococci.


This article has been cited by other articles:


Home page
 Antimicrob. Agents Chemother.Home page
V. C. Y. Chow, P. M. Hawkey, E. W. C. Chan, M. L. Chin, T. K. Au, D. K. C. Fung, and R. C. Y. Chan
High-Level Gentamicin Resistance Mediated by a Tn4001-Like Transposon in Seven Nonclonal Hospital Isolates of Streptococcus pasteurianus
Antimicrob. Agents Chemother., July 1, 2007; 51(7): 2508 - 2513.
[Abstract] [Full Text] [PDF]

Home page
 J Antimicrob ChemotherHome page
M. E. Falagas, D. K. Matthaiou, and I. A. Bliziotis
The role of aminoglycosides in combination with a {beta}-lactam for the treatment of bacterial endocarditis: a meta-analysis of comparative trials
J. Antimicrob. Chemother., April 1, 2006; 57(4): 639 - 647.
[Abstract] [Full Text] [PDF]

Home page
 J Antimicrob ChemotherHome page
J. C. Graham and F. K. Gould
Role of aminoglycosides in the treatment of bacterial endocarditis
J. Antimicrob. Chemother., March 1, 2002; 49(3): 437 - 444.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
INT J SYST EVOL MICROBIOL J MED MICROBIOL MICROBIOLOGY J GEN VIROL ALL SGM JOURNALS
Copyright © 1977 Society for General Microbiology.