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The Journal of Medical Microbiology, Vol 10, Issue 1 127-131, Copyright © 1977 by Society for General Microbiology

JOURNAL ARTICLE

A comparison of chloramphenicol and ampicillin as bactericidal agents for Haemophilus influenzae type B

D. C. Turk

In tests of bactericidal action against H. influenzae type b strains isolated from patients with meningitis, chloramphenicol was found to be far more reliable than ampicillin in dealing with large inocula, and more rapidly effective against both large and relatively small inocula. These findings provide a laboratory explanation for the somewhat better record of chloramphenicol as an agent for treatment of haemophilus meningitis.




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